Compound (S)-7, also known as PPARalpha/gamma agonist 4, is a dual potent agonist for PPARalpha and PPARgamma with EC50 values of 0.061 µM and 1.42 µM, respectively. This compound exhibits oral efficacy and operates through an insulin-independent mechanism, featuring mitochondrial pyruvate carrier inhibition and antidiabetic properties. PPARalpha/gamma agonist 4 holds potential for research in dyslipidemic type 2 diabetes.
Target:
PPAR
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