Antimycobacterial agent-8 (Compound 49) acts as an inhibitor of DNA gyrase (DNA gyrase). It exhibits antibacterial activity, with MIC90 values of 2.5 µM for Mycobacterium tuberculosis and 0.63 µM for M. abscessus. Additionally, Antimycobacterial agent-8 demonstrates effective plasma protein binding in mice.
Target:
Antibacterial|||DNA/RNA Synthesis
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