Adenosine receptor antagonist5 (Compound 39) serves as a selective antagonist for the human adenosine A3 receptor (hA3R) with a Ki of 12 nM. This compound inhibits the accumulation of IB-MECA-induced cAMP in NCI-H1792 cells and suppresses the proliferation of LK-2 and NCI-H1792 cancer cells. Additionally, Adenosine receptor antagonist5 exhibits a rapid metabolism rate in human liver microsomes.
Target:
Adenosine Receptor
* VAT and and shipping costs not included. Errors and price changes excepted