H-L-Phe(4-NH-Poc)-OH hydrochloride, CAS [[2737202-66-1]] Preis auf Anfrage

Product Overview

• Article Name: H-L-Phe(4-NH-Poc)-OH hydrochloride, CAS [[2737202-66-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T89698
• Supplier Catalog Number: T89698
• Alternative Catalog Number: TGM-T89698-10MG,TGM-T89698-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

H-L-Phe(4-NH-Poc)-OH (hydrochloride) is a chemical reagent utilized in the modification of phenylalanine or tyrosine analogues in protein and peptide biosynthesis. It contains an alkyne group, facilitating its role in copper-catalyzed azide-alkyne cycloaddition (CuAAC) with molecules that have azide groups. Commonly abbreviated as Poc or Pryoc, this compound acts as both a conventional click conjugation alkyne component and can be combined with tetrazine linkers in copper-free Diels-Alder type click reactions. Additionally, H-L-Phe(4-NH-Poc)-OH serves as a specialized protective group for amines, hydroxyl, and ester groups. Stable under neat trifluoroacetic acid (TFA), degradation occurs at room temperature using TFA:DCM with Co2(CO)8. Deprotection involving other transition metals such as palladium has also been reported.

Product Properties

• Molecular Weight: 298.72
• CAS Number: [2737202-66-1]
• Formula: C13H15ClN2O4
• Target: ADC Linker

Images

T89698