IKZF3 Degrader 1 (compound 19a) acts as an effective IKZF3 degrader with an EC50 of 0.012 µM and a minimal yield of 9.2%. It enhances the association of IKZF3 with Cereblon (CRBN), subsequently facilitating the ubiquitination and degradation of IKZF3.
Molecular Weight:
612.68
Formula:
C25H18BrCl3N2O5
Target:
Others|||IKZF|||Molecular Glues
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