LY 379196, a potent PKC-beta inhibitor (IC 50: 50 nM for PKC betaI and 30 nM for PKC betaII), effectively suppresses the proliferation of bovine retinal microvascular endothelial cells (BREC) induced by VEGF, IGF-1, and bFGF. This compound serves as an antiproliferative agent for proliferative retinopathy.
Molecular Weight:
562.68
Formula:
C30H34N4O5S
Target:
PKC
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