SR12343 is a small molecule inhibitor of the IKK/NF-kappaB signaling pathway that functions as a NEMO-binding domain (NBD) mimetic. SR12343 inhibits NF-kappaB activation with an IC50 of 37.02 µM by specifically blocking the critical IKKbeta-NEMO interaction, reduces pulmonary inflammation in models, and is suitable for research into inflammatory and degenerative diseases.
Molecular Weight:
368.66
Purity:
0.9991
CAS Number:
[2055101-86-3]
Formula:
C15H15BrClN3O
Target:
NF-kappaB|||IkappaB/IKK
T9055
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