Tuxobertinib (BDTX-189) is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations, with KDs of 0.2, 0.76, 13, and 1.2 nM for EGFR, HER2, BLK, and RIPK2, respectively, and exhibits anticancer activity.
Molecular Weight:
561.03
Purity:
0.9922
CAS Number:
[2414572-47-5]
Formula:
C29H29ClN6O4
Target:
RIP kinase|||HER|||EGFR|||BTK
T9072
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