Topovale, CAS [[500214-53-9]]

Product Overview

• Article Name: Topovale, CAS [[500214-53-9]]
• Biozol Catalog Number: TGM-T9088
• Supplier Catalog Number: T9088
• Alternative Catalog Number: TGM-T9088-1MG,TGM-T9088-5MG,TGM-T9088-10MG,TGM-T9088-25MG,TGM-T9088-50MG,TGM-T9088-100MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: ARC111 , ARC 111 , ARC-111 , Topoval

Product Description

Topovale (ARC111) is a potent inhibitor of topoisomerase I. Topovale inhibits hypoxia-mediated accumulation of hypoxia-inducible factor-1alpha. Topovale exhibited low nM cytotoxicity against a panel of cancer cells. Topovale cytotoxicity as well as Topovale-induced apoptosis was reduced > 100-fold in CPT-resistant topoisomerase I (TOP1)-deficient P388/CPT45 cells as compared with P388 cells.

Product Properties

• Molecular Weight: 421.45
• Purity: 0.9994
• CAS Number: [500214-53-9]
• Formula: C23H23N3O5
• Target: Topoisomerase

Images

T9088