N-piperidine Ibrutinib is a potent BTK inhibitor with IC50s of 51.0 for WT BTK and 30.7 nM for C481S BTK respectively. N-piperidine Ibrutinib can be used as a BTK ligand in the synthesis of a series of PROTACs, such as SJF620. SJF620 is a potent PROTAC BTK degrader with a DC50 of 7.9 nM.
Molecular Weight:
386.45
Purity:
96.65%
CAS Number:
[330785-90-5]
Formula:
C22H22N6O
Target:
Ligands for Target Protein for PROTAC|||BTK
T9408
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