TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK). It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 µM. Additionally, TNIK-IN-3 demonstrates inhibitory activity against Flt4 (IC50 = 0.030 µM), Flt1 (IC50 = 0.191 µM), and DRAK1 (IC50 = 0.411 µM). This compound holds potential for carrying out research on colorectal cancer (CRC) [1].
Molecular Weight:
387.41
Purity:
99.56%
CAS Number:
[2754265-25-1]
Formula:
C23H18FN3O2
Target:
DAPK|||Wnt/beta-catenin
T9556
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