GSK3685032 is a non-covalent and selective DNMT1 inhibitor(IC50 = 36 nM). The inhibitory effect is time-independent and reversible. GSK3685032 induces loss of DNA methylation and transcriptional activation and inhibits cancer cell growth.
Molecular Weight:
420.53
Purity:
99.49%
CAS Number:
[2170137-61-6]
Formula:
C22H24N6OS
Target:
DNA Methyltransferase
T9573
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