CU-115 is a selective and potent TLR8 antagonist with IC50 of 1.04 µM and =>50 µM for TLR8 and TLR7, respectively. CU-115 decreases production of TNF-alpha and IL-1beta activated by R-848 in THP-1 cells.
Molecular Weight:
569.21
Purity:
99.96%
CAS Number:
[2471982-20-2]
Formula:
C21H11F7INO2
Target:
TLR
T9645
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