AP-1/NF-kappaB activation inhibitor 1 is a potent inhibitor of AP-1 and NF-kappaB mediated transcriptional activation (IC50 = 1 µM), without blocking basal transcription driven by the beta-actin promoter. It has a similar inhibitory effect on the production of IL-2 and IL-8 levels in stimulated cells [1].
Molecular Weight:
344.25
Purity:
99.52%
CAS Number:
[188936-12-1]
Formula:
C13H11F3N4O4
Target:
NF-kappaB|||DNA/RNA Synthesis
T9656
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