Famitinib (SHR1020) is a potent orally active multi-targeted kinase inhibitor that effectively inhibits the activity of c-kit, VEGFR-2, and PDGFRbeta with IC50 values of 2.3 nM, 4.7 nM, and 6.6 nM, respectively [1]. It demonstrates remarkable antitumor properties in human gastric cancer cells and xenografts, inducing apoptosis [2].
Molecular Weight:
410.48
CAS Number:
[1044040-56-3]
Formula:
C23H27FN4O2
Target:
Others|||PDGFR|||VEGFR|||Apoptosis
T9665
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