EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual µ-opioid receptor (MOR) agonist and sigma1 receptor (sigma1R) antagonist, with K i s of 64 nM and 118 nM for MOR and sigma1R, respectively. EST73502 hydrochloride has antinociceptive activity with reduced opioid-induced relevant adverse events[1].
Molecular Weight:
388.88
CAS Number:
[2307458-82-6]
Formula:
C19H27ClF2N2O2
Target:
Opioid Receptor|||Others|||Sigma receptor
T9669
T9669
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