AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC).
Molecular Weight:
503.66
Purity:
99.87%
CAS Number:
[758722-49-5]
Formula:
C28H33N5O2S
Target:
Apoptosis|||Kinesin
T9682
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