JAK-IN-14 (compound 16) is a specific JAK1 inhibitor with IC50<5 µM. It prevents JAK1 phosphorylation by binding to the active site of JAK1, and is more than 8-fold selective for JAK1 over JAK2/JAK3, and can be used in immune, inflammation and cancer research.
Molecular Weight:
334.35
Purity:
98.27%
CAS Number:
[1973485-06-1]
Formula:
C19H15FN4O
Target:
JAK
T9764
T9764
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