Lu AF27139 is an effective and selective antagonist of P2X7 receptor (IC50s of 12 and 2.4 nM for human and rat, Kis of 22, 54, and 13 nM for mouse, human, and rat, respectively). Lu AF27139 can be used in CNS diseases studies.
Molecular Weight:
497.92
Purity:
0.9996
CAS Number:
[2097117-06-9]
Formula:
C21H19ClF3N5O2S
Target:
P2X Receptor
T9786
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