MKC-1 (Ro-31-7453) is an orally bioavailable small-molecule bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking mitotic spindle formation, which may result in apoptosis and tumor cell death.
Molecular Weight:
400.39
Purity:
98.38%
CAS Number:
[125313-92-0]
Formula:
C22H16N4O4
Target:
Microtubule Associated|||Akt|||mTOR|||Apoptosis
T9831
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