(E)-SI-2 is a potent small-molecule inhibitor of steroid receptor coactivator-3 (SRC-3 or AIB1) that can selectively inhibit the intrinsic transcriptional activities of SRC-3, also inhibits SRC-1 and SRC-2. It selectively reduces cellular protein levels of SRC-3, but not that of CARM-1, blocks MDA-MB-468 cell growth with an IC50 value of 3.4 nM, but spares normal cells.
Molecular Weight:
265.31
Purity:
99.80%
CAS Number:
[380537-35-9]
Formula:
C15H15N5
Target:
Others
T9836
* VAT and and shipping costs not included. Errors and price changes excepted