TXB4 is a human monoclonal antibody (mAb) that penetrates the brain and targets CD71. In a mouse model of Parkinsons disease (PD) induced by 6-OHDA, TXB4 prevents 6-OHDA-induced death of TH-positive neurons in the SNc. TXB4 can be utilized for studies on neurodegenerative diseases, acute brain and spinal cord injuries, and depression.
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