PLX-4545 has oral biological activity and is a cereblon based IKZF2 (zinc finger transcription factor Helios) molecular gel degrading agent that acts on immune suppressive regulatory T cells, reprogramming them into pro-inflammatory effector T cells and enhancing anti-tumor immune response.
Molecular Weight:
473.56
CAS Number:
[2892065-45-9]
Formula:
C28H31N3O4
Target:
Molecular Glues|||Ligand for E3 Ligase
T9901A-102
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