MG-1131 is a human monoclonal antibody (mAb) targeting TIGIT. It activates NF-kappaB signaling in T cells and enhances NK cell-mediated tumor-killing activity in a PVR-dependent manner. By blocking TIGIT, MG-1131 increases IFN-gamma secretion. This compound is applicable for research in antitumor immunity. Recommended isotype control: HumanIgG1kappa, Isotype Control.
Target:
NF-kappaB|||Others|||IFNAR
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