Lpathomab (LT3015, LT-3000) is a human IgG1 monoclonal antibody (mAb) targeting LPA. It reduces the release of cytokines IL-8 and IL-6 in SKOV3 cells and blocks tumor cell migration triggered by LPA. In Matrigel plug and CNV models, Lpathomab decreases angiogenesis. In the CCI mouse model, it inhibits brain injury. This compound can be utilized for research on brain injury, ovarian cancer, diabetic neuropathy, and spinal cord injury. Recommended isotype control: HumanIgG1kappa, Isotype Control.
CAS Number:
[1253114-37-2]
Target:
LPL Receptor
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