PF-04840082 is a humanized IgG2 monoclonal antibody inhibitor targeting Dkk-1. It binds to the physiological antagonist (Dkk-1) of the Wnt/LRP5 signaling pathway, which enhances bone mass and density by activating osteoblasts. PF-04840082 is applicable for osteoporosis research.
Target:
Wnt/beta-catenin
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