YS110 is a humanized anti-CD26 (DPP4) IgG1 monoclonal antibody. It induces CD26 nuclear translocation via the caveolin pathway and inhibits tumor cell proliferation by delaying the G2/M cell cycle transition. Additionally, YS110 blocks the binding of MERS CoV S1 to CD26, thereby preventing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection. This compound is applicable in research on cancer and infections, including malignant mesothelioma and MERS.
CAS Number:
[1656248-21-3]
Target:
Proteasome|||p38 MAPK|||ERK
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