HB-0017 is a humanized IgG1kappa monoclonal antibody inhibitor that targets IL-17A. It effectively blocks IL-17A-induced IL-6 secretion with an IC50 of 2.09 nM. In psoriatic-like mouse models induced by Imiquimod, HB-0017 significantly reduces auricular thickness and alleviates inflammation in arthritis and air pouch mouse models caused by IL-17A. For isotype control, refer to Human IgG1 kappa, Isotype Control.
CAS Number:
[2790610-50-1]
Target:
Interleukin
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