AGS-009 is a humanized monoclonal neutralizing antibody that targets IFN-alpha. It significantly reduces the number of activated lymphocytes (e.g., CD4+ and CD8+ T cells as well as B cells) in a SIV-infected rhesus monkey model. AGS-009 is applicable to research on autoimmune diseases such as systemic lupus erythematosus (SLE) and HIV infection.
Target:
IFNAR|||HIV Protease
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