LY-2624587, CAS [[2125546-89-4]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T9901A-1919
Supplier Catalog Number:
T9901A-1919
Alternative Catalog Number:
TGM-T9901A-1919-1MG,TGM-T9901A-1919-5MG
Manufacturer:
TargetMol
Category:
Biochemikalien
LY-2624587 is a humanized IgG4 monoclonal antibody antagonist targeting CXCR4. It effectively blocks the interaction between SDF-1 and CXCR4, as well as SDF-1-induced GTP binding. LY-2624587 significantly inhibits cellular migration and induces apoptosis in human lymphoma and leukemia cells. Additionally, LY-2624587 suppresses cell signaling mediated by CXCR4 and SDF-1, including MAPK and AKT activation. This compound is utilized in research on human hematological malignancies, such as acute myeloid leukemia (AML).
CAS Number:
[2125546-89-4]
Target:
p38 MAPK|||Akt|||Apoptosis|||CXCR
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