H2N-PEG-SH (MW 5000) is a linear heterobifunctional polyethylene glycol derivative containing both thiol and amine groups. H2N-PEG-SH (MW 10000) serves as a crucial crosslinking or bioconjugation agent featuring a PEG chain. The thiol group (?SH), or mercapto group, selectively reacts with maleimide, OPSS, vinyl sulfone, and transition metal surfaces (including gold and silver).
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