Fmoc-PEG-Maleimide (MW 5000) (Fmoc-NH-PEG-Mal (MW 5000)) is a PEG derivative featuring an Fmoc protective group and a Maleimide reactive group. Fmoc serves as a widely used amine-protecting group, shielding amines from undesirable reactions until specific coupling is needed. Maleimide reacts with thiols (-SH) to form stable thioether bonds. PEG modification enhances solubility and stability while reducing the immunogenicity of proteins and peptides.
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