Rapamycin is a potent and specific mTOR inhibitor that suppresses mTOR in HEK293 cells with an IC50 of 0.1 nM. It binds to FKBP12, thereby inhibiting mTORC1. Additionally, Rapamycin serves as an autophagy (autophagy) activator and functions as an immunosuppressant.
Target:
mTOR|||Autophagy|||FKBP
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