N-Acetyl-D-mannosamine-15N is the 15N-labeled version of N-Acetyl-D-mannosamine (ManNAc). This compound serves as an essential precursor for N-acetylneuraminic acid (NeuAc) and acts as a specific monomer in bacterial capsular poly(sialic acid) [PA]. N-Acetyl-D-mannosamine (ManNAc) is metabolized by GNE and GlcNAc 2-epimerase (renin-binding protein, RnBP) into ManNAc-6-phosphate and GlcN.
Target:
Antibacterial
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