Dolutegravir-d5, CAS [[2249814-82-0]] Preis auf Anfrage

Product Overview

• Article Name: Dolutegravir-d5, CAS [[2249814-82-0]] Preis auf Anfrage
• Biozol Catalog Number: TGM-TMID-0752
• Supplier Catalog Number: TMID-0752
• Alternative Catalog Number: TGM-TMID-0752-10MG,TGM-TMID-0752-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Dolutegravir-d5 is the deuterated form of Dolutegravir. Dolutegravir (S/GSK1349572) is a potent, orally administered HIV integrase strand transfer inhibitor, with an IC50 of 2.7 nM in the chain-transfer catalyzed by HIV-1 integrase. It effectively inhibits the replication of HIV-1 in peripheral blood mononuclear cells with an IC50 of 0.51 nM. Additionally, Dolutegravir (S/GSK1349572) remains effective against Y143R, N155H, and G140S/Q148H mutants, with an EC50 ranging from 3.6 to 5.8 nM.

Product Properties

• Molecular Weight: 424.41
• CAS Number: [2249814-82-0]
• Formula: C20H19F2N3O5
• Target: HIV Protease

Images

TMID-0752