ABT-737-d8, CAS [[1217686-68-4]] Preis auf Anfrage
Biozol Catalog Number:
TGM-TMID-0820
Supplier Catalog Number:
TMID-0820
Alternative Catalog Number:
TGM-TMID-0820-10MG,TGM-TMID-0820-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
ABT 737-d8 is the deuterated form of ABT-737, a BH3 mimetic and potent inhibitor of Bcl-2, Bcl-xL, and Bcl-w, with EC50 values of 30.3 nM, 78.7 nM, and 197.8 nM respectively. ABT-737 disrupts the BCL-2/BAX complex and activates the intrinsic apoptotic pathway in a BAK-dependent and BIM-independent manner. Additionally, ABT-737 induces autophagy and shows potential for research in acute myeloid leukemia (AML).
Molecular Weight:
821.48
CAS Number:
[1217686-68-4]
Formula:
C42H45ClN6O5S2
Target:
Others
TMID-0820
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