Nadolol-d9 (Mixture of Diastereomers), CAS [[1432056-38-6]] Preis auf Anfrage
Biozol Catalog Number:
TGM-TMIJ-0317
Supplier Catalog Number:
TMIJ-0317
Alternative Catalog Number:
TGM-TMIJ-0317-1MG,TGM-TMIJ-0317-5MG
Manufacturer:
TargetMol
Category:
Biochemikalien
Nadolol-d9 (Mixture of Diastereomers) is a deuterated compound of Nadolol. Nadolol has a CAS number of 42200-33-9. Nadolol is a non-selective beta-adrenergic antagonist with antihypertensive and antiarrhythmic activities. Nadolol competitively blocks beta-1 adrenergic receptors located in the heart and vascular smooth muscle, inhibiting the activities of the catecholamines epinephrine and norepinephrine and producing negative inotropic and chronotropic effects. This agent exhibits antiarrhythmic activity via the impairment of atrioventricular (AV) node conduction and a corresponding reduction in sinus rate. In the kidney, inhibition of the beta-2 receptor within the juxtaglomerular apparatus results in the inhibition of renin production and a subsequent reduction in angiotensin II and aldosterone levels, thus inhibiting angiotensin II-dependent vasoconstriction and aldosterone-dependent water retention.
Molecular Weight:
636.91
CAS Number:
[1432056-38-6]
Formula:
C34H36D18N2O8
TMIJ-0317
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