HMG-CoA reductase , 3-hydroxy-3-methylglutaryl-coenzyme A reductase , HMGCR
Catalyzes the conversion of (3S)-hydroxy-3-methylglutaryl-CoA (HMG-CoA) to mevalonic acid, the rate-limiting step in the synthesis of cholesterol and other isoprenoids, thus plays a critical role in cellular cholesterol homeostasis. HMGCR is the main target of statins, a class of cholesterol-lowering drugs.
Purity:
91.00%
TMPH-00007
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