Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)

Product Overview

• Article Name: Delta-AITX-Avd1c Protein, Anemonia sulcata, Recombinant (His)
• Biozol Catalog Number: TGM-TMPH-00056
• Supplier Catalog Number: TMPH-00056
• Alternative Catalog Number: TGM-TMPH-00056-1MG,TGM-TMPH-00056-5UG,TGM-TMPH-00056-10UG,TGM-TMPH-00056-20UG,TGM-TMPH-00056-50UG,TGM-TMPH-00056-100UG,TGM-TMPH-00056-200UG,TGM-TMPH-00056-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Neurotoxin 2 , Toxin II , Anemonia sulcata toxin 2 (As2) , Delta-actitoxin-Avd1c , ATX-II (ATX II) , Delta-AITX-Avd1c

Product Description

Binds specifically to voltage-gated sodium channels (Nav) (site 3), thereby delaying their inactivation. Has a strong effect on crustaceans and insects (DmNav1) and a weaker effect on mammals. This toxin is highly potent at mammalian Nav1.1/SCN1A (EC(50)=6.01 nM) and Nav1.2/SCN2A (EC(50)=7.88 nM). It has also great activity on Nav1.5/SCN5A (EC(50)=49.05 nM), Nav1.4/SCN4A (EC(50)=109.49 nM) and Nav1.6/SCN8A (EC(50)=about 180 nM) and is less potent on Nav1.3/SCN3A (EC(50)=759.22 nM) (when measured as the increase in the slow component).

Product Properties

• Molecular Weight: 6.9 kDa (predicted)

Images

TMPH-00056