stx2A , Verotoxin 2 subunit A , stxA2 , SLT-IIa , Verocytotoxin 2 subunit A , rRNA N-glycosidase 2 , SLT-2 A subunit , SLT-2a , Shiga-like toxin 2 subunit A
The A subunit is responsible for inhibiting protein synthesis through the catalytic inactivation of 60S ribosomal subunits. After endocytosis, the A subunit is cleaved by furin in two fragments, A1 and A2: A1 is the catalytically active fragment, and A2 is essential for holotoxin assembly with the B subunits.
Molecular Weight:
40.6 kDa (predicted)
TMPH-00516
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