GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2,3-cyclic-phosphate or 3-phosphate ends to RNA with 5-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splicing dirty DNA breaks, characterized by 3-phosphate (or cyclic-phosphate) and 5-hydroxy ends that cannot be sealed by classical DNA ligases.
TMPH-00732
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