Aggrecanase-1 , ADAM-TS 4 , KIAA0688 , ADAMTS4 , ADAM-TS4 , ADAMTS-4 , A disintegrin and metalloproteinase with thrombospondin motifs 4 , ADMP-1
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. Could also be a critical factor in the exacerbation of neurodegeneration in Alzheimer disease. Cleaves aggrecan at the 392-Glu-|-Ala-393 site. ADAMTS4 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 39.0 kDa and the accession number is O75173.
TMPH-00867
* VAT and and shipping costs not included. Errors and price changes excepted