GCKR Protein, Human, Recombinant (His)

Product Overview

• Article Name: GCKR Protein, Human, Recombinant (His)
• Biozol Catalog Number: TGM-TMPH-01387
• Supplier Catalog Number: TMPH-01387
• Alternative Catalog Number: TGM-TMPH-01387-1MG,TGM-TMPH-01387-5UG,TGM-TMPH-01387-10UG,TGM-TMPH-01387-20UG,TGM-TMPH-01387-50UG,TGM-TMPH-01387-100UG,TGM-TMPH-01387-200UG,TGM-TMPH-01387-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: GCKR , GKRP , Glucokinase regulatory protein , Glucokinase regulator

Product Description

Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. GCKR Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 70.7 kDa and the accession number is Q14397.

Images

TMPH-01387