GCKR Protein, Human, Recombinant (His & SUMO)

Product Overview

• Article Name: GCKR Protein, Human, Recombinant (His & SUMO)
• Biozol Catalog Number: TGM-TMPH-01388
• Supplier Catalog Number: TMPH-01388
• Alternative Catalog Number: TGM-TMPH-01388-1MG, TGM-TMPH-01388-5UG, TGM-TMPH-01388-10UG, TGM-TMPH-01388-20UG, TGM-TMPH-01388-50UG, TGM-TMPH-01388-100UG, TGM-TMPH-01388-200UG, TGM-TMPH-01388-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Glucokinase regulator , Glucokinase regulatory protein , GCKR , GKRP

Product Description

Regulates glucokinase (GCK) by forming an inactive complex with this enzyme. Acts by promoting GCK recruitment to the nucleus, possibly to provide a reserve of GCK that can be quickly released in the cytoplasm after a meal. The affinity of GCKR for GCK is modulated by fructose metabolites: GCKR with bound fructose 6-phosphate has increased affinity for GCK, while GCKR with bound fructose 1-phosphate has strongly decreased affinity for GCK and does not inhibit GCK activity. GCKR Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 84.7 kDa and the accession number is Q14397.

Images

TMPH-01388