Heat shock protein 75 kDa, mitochondrial , mitochondrial , TNFR-associated protein 1 , Tumor necrosis factor type 1 receptor-associated protein (TRAP-1) , HSP 75 , Heat shock protein family C member 5 , HSP75 , TRAP1 , HSPC5
Chaperone that expresses an ATPase activity. Involved in maintaining mitochondrial function and polarization, downstream of PINK1 and mitochondrial complex I. Is a negative regulator of mitochondrial respiration able to modulate the balance between oxidative phosphorylation and aerobic glycolysis. The impact of TRAP1 on mitochondrial respiration is probably mediated by modulation of mitochondrial SRC and inhibition of SDHA. TRAP1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 54.5 kDa and the accession number is Q12931.
TMPH-01428
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