Interferon alpha-inducible protein 6 , G1P3 , Interferon-induced protein 6-16 (Ifi-6-16) , IFI6
Plays a role in apoptosis, negatively regulating the intrinsinc apoptotic signaling pathway and TNFSF10-induced apoptosis. However, it has also been shown to have a pro-apoptotic activity. Has an antiviral activity towards hepatitis C virus/HCV by inhibiting the EGFR signaling pathway, which activation is required for entry of the virus into cells.
TMPH-01548
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