Protein MIG-5 , Tissue inhibitor of metalloproteinases 3 (TIMP-3) , TIMP3 , Metalloproteinase inhibitor 3
Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
TMPH-01665
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