Protein unc-18 homolog 1 (Unc18-1) , Protein unc-18 homolog A (Unc-18A) , Syntaxin-binding protein 1 , UNC18A , p67 , STXBP1 , MUNC18-1 , N-Sec1
Participates in the regulation of synaptic vesicle docking and fusion through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
TMPH-02166
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