YjeF_N3 , AIBP2 , YJEFN3 , YjeF N-terminal domain-containing protein 3 , hYjeF_N3 , ApoA-I-binding protein 2
May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endothelium, a type of specialized endothelium manifesting hematopoietic potential. YJEFN3-mediated cholesterol efflux activates endothelial SREBF2, the master transcription factor for cholesterol biosynthesis, which in turn transactivates NOTCH and promotes hematopoietic stem and progenitor cell emergence. May play a role in spermiogenesis and oogenesis.
Molecular Weight:
32.6 kDa (predicted)
TMPH-02316
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