Granzyme A/GZMA Protein, Mouse, Recombinant (His)

Product Overview

• Article Name: Granzyme A/GZMA Protein, Mouse, Recombinant (His)
• Biozol Catalog Number: TGM-TMPH-02687
• Supplier Catalog Number: TMPH-02687
• Alternative Catalog Number: TGM-TMPH-02687-1MG,TGM-TMPH-02687-5UG,TGM-TMPH-02687-10UG,TGM-TMPH-02687-20UG,TGM-TMPH-02687-50UG,TGM-TMPH-02687-100UG,TGM-TMPH-02687-200UG,TGM-TMPH-02687-500UG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: CTLA-3 , T cell-specific serine protease 1 (TSP-1) , Autocrine thymic lymphoma granzyme-like serine protease , Granzyme A , Ctla-3 , Ctla3 , Gzma , Mtsp-1 , Fragmentin-1

Product Description

Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after Lys-31 and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after Lys-189, which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA. Granzyme A/GZMA Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 31.6 kDa and the accession number is P11032.

Product Properties

• Molecular Weight: 31.6 kDa (predicted)

Images

TMPH-02687